作者: José Luis Pasquel Reátegui , Francisco Manuel Barrales , Camila A. Rezende , Carmen L. Queiroga , Julian Martínez
DOI: 10.1016/J.INDCROP.2017.06.027
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摘要: Abstract The oleoresin of copaiba has many pharmacological properties, such as anti-inflammatory, antiseptic, and cicatrizing, besides helping to treat skin diseases, among other applications. In order improve its activity, was encapsulated within polymeric particles through emulsification assisted by ultrasound followed a drying process. Ultrasound-assisted led the formation kinetically stable emulsions. emulsions with increased stability lowest droplet diameters (80.95 ± 2.1 nm (Hi-Cap 100®) 71.8 ± 2.9 nm (Snow-Flake® E 6131)) were subjected freeze-drying spray-drying produce dry particles. characterized in terms moisture content, particle size distribution, encapsulation efficiency, surface oil, oxidative stability, X-ray diffraction morphological analysis FESEM CLSM. Both techniques produced amorphous different sizes low content. Furthermore, high efficiency against thermal degradation achieved. particles’ morphology indicated that nature biopolymers used 100® Snow-Flake® 6131) did not affect their microstructure. However, expected, external microstructures. SD spherical, whereas FD presented irregular structures similar sheets.