Studies on the active constituents of Momordica charantia L

摘要: Five compounds were isolated from the seeds of Momordica charantia. This paper reports their structure determination by spectral (IR, UV, HNMR, CNMR, and MS) chemical methods. The structures I, II, III, IV V elucidated as vacine, mycose, 3-O-(beta-D-glucopyranosyl)-24 beta-ethyl-5 alpha-cholesta-7, trans-22E, 25 (27)-trien-3 beta-ol, momorcharaside A B respectively. Mycose was first time found in this plant compound III genus Momordica. new compounds. exhibited obvious inhibition DNA RNA syntheses S 180 tumor cells preliminary pharmacological studies.