Mechanisms of tau-induced neurodegeneration

作者: Fei Liu , Cheng-Xin Gong , Alejandra del C. Alonso , Inge Grundke-Iqbal , Khalid Iqbal

DOI: 10.1007/S00401-009-0486-3

关键词:

摘要: … The AD cytosolic abnormally hyperphosphorylated tau (AD P-tau) does not bind to tubulin and promote microtubule assembly, but instead it inhibits assembly and disrupts microtubules […

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