Subtypes of vascular dementia.

摘要: The challenge of describing subgroups is particularly important in vascular dementia, which, contrast to more stereotypic processes affecting cognitive function, better thought as several syndromes rather than a disease. Many current diagnostic descriptions lack strong empiric basis. Some the categories now use suffer from priori assumptions about causality and pattern associations, which themselves have not been validated. so-called mixed dementia syndrome may underrepresented our estimation subtypes, comparison with pure causes. Within syndrome, whether seen isolation or combination other causes relative contributions white matter changes compared multiple cortical strokes needs be clarified. It remains controversy prolonged chronic intermittent cerebral ischemia statistically part dementia. variable relation between clinical presentation neuroimaging localization has consequences for understanding pathophysiology impairment arising Recent data also suggest that we should focus away both Alzheimer disease model multi-infarct There are opportunities available clinicians many disciplines collaborate precise large numbers patients advance spectrum impairment.