Polymer coated phosphate glass/hydroxyapatite composite scaffolds for bone tissue engineering applications
作者： R. Govindan , G. Suresh Kumar , E. K. Girija
DOI: 10.1039/C5RA09258B
关键词:
摘要: The development of bioactive ceramic composite scaffold materials with enhanced mechanical strength has been a topic great interest in bone tissue engineering. In the present study, phosphate glass/hydroxyapatite (PG/HA) an open-porous structure (∼89% porosity and pore size range 200–500 μm) fabricated by polymer foam replication method. order to enhance this scaffold, coating alginate, chitosan gelatin was made on immersion did not affect interconnectivity but reduced PG/HA scaffold. Biodegradation studies revealed that all scaffolds have undergone significant degradation. But compressive coated (G-PG/HA) exhibited sevenfold enhancement than pristine G-PG/HA excellent biocompatibility human osteoblast-like MG-63 cells. Hence, may be smart promising for
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