General Platform for the Conversion of Isoxazol‐5‐ones to 3,5‐Disubstituted Isoxazoles via Nucleophilic Substitutions and Palladium Catalyzed Cross‐Coupling Strategies

作者: Alessandra A. G. Fernandes , Amanda F. da Silva , Celso Y. Okada , Vitor Suzukawa , Rodrigo A. Cormanich

DOI: 10.1002/EJOC.201900187

关键词:

摘要:

参考文章(62)
Feng Hu, Michal Szostak, Recent Developments in the Synthesis and Reactivity of Isoxazoles: Metal Catalysis and Beyond Advanced Synthesis & Catalysis. ,vol. 357, pp. 2583- 2614 ,(2015) , 10.1002/ADSC.201500319
R.V. Stevens, K.F. Albizati, Synthesis and nucleophilic substitutions of 3-alkyl-5-chloroisoxazoles Tetrahedron Letters. ,vol. 25, pp. 4587- 4590 ,(1984) , 10.1016/S0040-4039(01)91206-7
Ahmed Kamal, J Surendranadha Reddy, M Janaki Ramaiah, D Dastagiri, E Vijaya Bharathi, M Ameruddin Azhar, Farheen Sultana, SNCVL Pushpavalli, Manika Pal-Bhadra, Aarti Juvekar, Subrata Sen, Surekha Zingde, Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents. European Journal of Medicinal Chemistry. ,vol. 45, pp. 3924- 3937 ,(2010) , 10.1016/J.EJMECH.2010.05.047
R. Krishma Mohan Rao Kallury, P.S. Uma Devi, Vilsmeier-haack reaction of 5(4H)-isoxazolones Tetrahedron Letters. ,vol. 18, pp. 3655- 3658 ,(1977) , 10.1016/S0040-4039(01)83318-9
Shibing Tang, Jinmei He, Yongquan Sun, Liuer He, Xuegong She, Efficient and regioselective one-pot synthesis of 3-substituted and 3,5-disubstituted isoxazoles. Organic Letters. ,vol. 11, pp. 3982- 3985 ,(2009) , 10.1021/OL901626N
HIROSHI YAMANAKA, MASAFUMI SHIRAIWA, ETSUKO YAMAMOTO, TAKAO SAKAMOTO, Cross-coupling Reactions of Haloisoxazoles with Olefins and Acetylenes Chemical & Pharmaceutical Bulletin. ,vol. 29, pp. 3543- 3547 ,(1981) , 10.1248/CPB.29.3543
Ryo Harigae, Katsuhiko Moriyama, Hideo Togo, Preparation of 3,5-Disubstituted Pyrazoles and Isoxazoles from Terminal Alkynes, Aldehydes, Hydrazines, and Hydroxylamine Journal of Organic Chemistry. ,vol. 79, pp. 2049- 2058 ,(2014) , 10.1021/JO4027116
Fahmi Himo, Timothy Lovell, Robert Hilgraf, Vsevolod V. Rostovtsev, Louis Noodleman, K. Barry Sharpless, Valery V. Fokin, Copper(I)-Catalyzed Synthesis of Azoles. DFT Study Predicts Unprecedented Reactivity and Intermediates Journal of the American Chemical Society. ,vol. 127, pp. 210- 216 ,(2005) , 10.1021/JA0471525
Igor Dias-Jurberg, Fabien Gagosz, Samir Z. Zard, Unusual Approach to Branched 3-Alkynylamides and to 1,5-Dihydropyrrol-2-ones Organic Letters. ,vol. 12, pp. 416- 419 ,(2010) , 10.1021/OL902472R