Vitamin D and cardiovascular disease risk: emerging evidence.

摘要: Purpose of review Vitamin D deficiency is common throughout the world, with a particularly high prevalence in northern latitudes and colder climates. Although best known sequelae vitamin involve musculoskeletal system, growing body evidence suggests that status may influence cardiovascular health as well. This focuses on recent studies linking disease risk, emphasizing potential relevance to primary prevention. Recent findings There strong experimental structure function. The number clinical has steadily grown years, largest comprising observational showing associations between low status, presence various risk factors, adverse outcomes. A few small, randomized, controlled have been published, but these largely inconclusive. Summary Despite substantial increased it remains be established whether this represents causal association. Further study needed prospective, randomized trials before supplementation can routinely recommended for or secondary prevention disease.