Precocious Puberty: Pathophysiology and Treatment
作者： Selna L. Kaplan , David Stephure , Jasna Knezvic , Melvin M. Grumbach
DOI: 10.1007/978-94-009-0725-6_8
关键词:
摘要: Pubertal maturation can be defined as the reactivation or disinhibition of a suppressed hypothalamic GnRH pulse generator system. Increased amplitude pulsatile release and increased stimulation pituitary gonadotropes, particularly at night, results in gonadal secretion [1–3].
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