Hostility and helper T-cells in patients with bulimia nervosa

摘要: OBJECTIVE: The study aimed to analyze the correlation between lymphocyte counts and several psychopathological variables associated with psychological instability (depression, hostility, impulsivity, self-defeating personality traits, borderline symptoms) in patients bulimia nervosa (BN). METHOD: Sixty BN were assessed, using specific scales for eating pathology, general psychopathology, depression, features. Lymphocyte subset performed. Plasma cortisol at 8:00, before after administration of 1mg dexamethasone 23:00, was determined. influence body weight, use tobacco, alcohol, caffeine controlled. relationship each isolated variable number immune cells analyzed. In a second step, supplementary post-hoc analysis introduced confirm accuracy assessment. RESULTS: Hostility negatively correlated helper T-cells (CD4+). Patients high hostility had lower CD4+ cell CD4+/CD8+ ratios. control study, significantly related other “interpersonal” items. CONCLUSIONS: These results support idea that as an expression disturbed interpersonal relationships, could play role modulator activity BN.