Breast lesions: correlation of contrast medium enhancement patterns on MR images with histopathologic findings and tumor angiogenesis.

摘要: PURPOSE: To compare qualitative and quantitative magnetic resonance (MR) mammographic features of breast lesions with histopathologic findings, especially tumor angiogenesis. MATERIALS AND METHODS: Seventy-three patients (72 women, one man; aged 30-78 years; mean age, 51.0 years) suspicious underwent MR imaging. Noncontrast medium-enhanced localization imaging then gadolinium-enhanced dynamic fast spoiled gradient-recalled-echo (SPGR) were performed in all patients. In selected patients, subtraction SPGR images obtained. The Pearson Spearman correlation tests used to determine the strength relationships between enhancement parameters microvessel determinations. RESULTS: Time intensity curve type correlated density grade (Spearman rank test: r = .90, P < .001). steepest slope contrast medium uptake counts (Pearson test; .83, Peripheral invas...