Marked pericardial inhomogeneity of specific ventilation at total lung capacity and beyond.

作者: Yanping Sun , James P. Butler , Peter Lindholm , Ronn P. Walvick , Stephen H. Loring

DOI: 10.1016/J.RESP.2009.07.024

关键词:

摘要: We measured regional ventilation at 1 liter above functional residual capacity (FRC+1L) and total lung (TLC) in three normal subjects four elite breath-hold divers, TLC after glossopharyngeal insufflation (TLC+GI) the divers. Hyperpolarized 3He MRI was used to map local per unit volume over entire lung. At above, there markedly increased of lungs pericardial region compared with relatively uniform throughout rest The distribution fractional regionally FRC+1L, a small non-gravitational cephalocaudal gradient specific supine posture. Our observations high volumes are consistent effect pleural tension concave region, which promotes expansion subjacent lung, leading higher effective compliance ventilation.

参考文章(17)
M. A. Hajji, T. A. Wilson, S. J. Lai-Fook, Improved measurements of shear modulus and pleural membrane tension of the lung Journal of Applied Physiology. ,vol. 47, pp. 175- 181 ,(1979) , 10.1152/JAPPL.1979.47.1.175
W. Happer, E. Miron, S. Schaefer, D. Schreiber, W. A. van Wijngaarden, X. Zeng, Polarization of the nuclear spins of noble-gas atoms by spin exchange with optically pumped alkali-metal atoms Physical Review A. ,vol. 29, pp. 3092- 3110 ,(1984) , 10.1103/PHYSREVA.29.3092
M Nygren-Bonnier, K Wahman, P Lindholm, A Markström, N Westgren, B Klefbeck, Glossopharyngeal pistoning for lung insufflation in patients with cervical spinal cord injury. Spinal Cord. ,vol. 47, pp. 418- 422 ,(2009) , 10.1038/SC.2008.138
Peter Lindholm, Charles M. Norris, John M. Braver, Francine Jacobson, Massimo Ferrigno, A fluoroscopic and laryngoscopic study of glossopharyngeal insufflation and exsufflation Respiratory Physiology & Neurobiology. ,vol. 167, pp. 189- 194 ,(2009) , 10.1016/J.RESP.2009.04.013
Stephen H. Loring, Carl R. O'Donnell, James P. Butler, Peter Lindholm, Francine Jacobson, Massimo Ferrigno, Transpulmonary pressures and lung mechanics with glossopharyngeal insufflation and exsufflation beyond normal lung volumes in competitive breath-hold divers. Journal of Applied Physiology. ,vol. 102, pp. 841- 846 ,(2007) , 10.1152/JAPPLPHYSIOL.00749.2006
R. W. Glenny, W. J. Lamm, R. K. Albert, H. T. Robertson, Gravity is a minor determinant of pulmonary blood flow distribution Journal of Applied Physiology. ,vol. 71, pp. 620- 629 ,(1991) , 10.1152/JAPPL.1991.71.2.620
Yang-Sheng Tzeng, Kenneth Lutchen, Mitchell Albert, The difference in ventilation heterogeneity between asthmatic and healthy subjects quantified using hyperpolarized 3He MRI Journal of Applied Physiology. ,vol. 106, pp. 813- 822 ,(2009) , 10.1152/JAPPLPHYSIOL.01133.2007
Talissa A Altes, Patrice K Rehm, Frank Harrell, Michael Salerno, Thomas M Daniel, Eduard E de Lange, Ventilation imaging of the lung: Comparison of hyperpolarized helium-3 MR imaging with Xe-133 scintigraphy1 Academic Radiology. ,vol. 11, pp. 729- 734 ,(2004) , 10.1016/J.ACRA.2004.04.001
Leigh M. Seccombe, Peter G. Rogers, Nghi Mai, Chris K. Wong, Leonard Kritharides, Christine R. Jenkins, Features of glossopharyngeal breathing in breath-hold divers. Journal of Applied Physiology. ,vol. 101, pp. 799- 801 ,(2006) , 10.1152/JAPPLPHYSIOL.00075.2006