Chapter 12 – Biomedical applications of inductively coupled plasma mass spectrometry (ICP–MS) as an element specific detector for chromatographic separations

摘要: This chapter discusses the biomedical applications of inductively coupled plasma mass spectrometry (ICP-MS) as an element specific detector for chromatographic separations. Typically, in ICP, gas flows into three concentric tubes. These tubes are assembled together what is commonly referred to torch. ICP-MS a powerful analytic technique that finding popularity The has rapidly matured choice routine ultra trace-element analysis. mainly due its advantages terms detection limits, relative freedom from interference, and speed opened door novel research field investigating metabolic fate drugs, phosphorylation reactions, role essential trace elements human health, mechanisms which toxic affect body. offers selectivity, sensitivity, quantitative determinations and, such, it gaining acceptance tool pharmaceutical research.