Analysis of iodinated X-ray contrast agents in water samples by ion chromatography and inductively-coupled plasma mass spectrometry.

作者: Frank Sacher , Brigitte Raue , Heinz-Jürgen Brauch

DOI: 10.1016/J.CHROMA.2005.01.031

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摘要: Abstract In this paper, an analytical method for the determination of six iodinated X-ray contrast agents (amidotrizoic acid, iohexol, iomeprol, iopamidol, iopromide, and ioxitalamic acid), iodide, iodate in water samples is presented. The based on a separation analytes by ion chromatography (IC) subsequent detection inductively-coupled plasma mass spectrometry (ICP-MS). was optimised with respect to conditions (column type eluent composition) extensively validated. Without pre-concentration samples, limits below 0.2 μg/l could be achieved whereby reproducibility 6% all compounds under investigation.

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