作者: N D Freedman , A Schatzkin , M F Leitzmann , A R Hollenbeck , C C Abnet
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摘要: We investigated the relation between head and neck cancer risk alcohol consumption in NIH-AARP Diet Health Study. During 2 203 500 person-years of follow-up, 611 men 183 women developed cancer. With moderate drinking (up to one alcoholic drink per day) as referent group, non-drinkers showed an increased (men: hazard ratio (HR) 1.68, 95% confidence interval (95% CI) 1.37–2.06; women: 1.46, 1.02–2.08). Among male female drinkers, we observed a significant dose–response relationship risk. The HR for consuming >3 drinks day was significantly higher (2.52, 1.46–4.35) than (1.48, 1.15–1.90; P interaction=0.0036). incidence rates 100 000 those who consumed were similar (77.6) (75.3). HRs resulted from lower group: (14.7), (34.4). In summary, beverages associated with women, but up may be reduced relative non-drinking.