A review of the possible role of the essential fatty acids and fish oils in the aetiology, prevention or pharmacotherapy of schizophrenia
作者： K. Akter , D. A. Gallo , S. A. Martin , N. Myronyuk , R. T. Roberts
DOI: 10.1111/J.1365-2710.2011.01265.X
关键词:
摘要: Summary What is known and Objective: Fish oils other essential fatty acids have been purported to ameliorate the symptoms of schizophrenia or adverse effects drugs that are used manage it. Our objective review basic clinical evidence regarding replenishment reported decreased levels polyunsaturated acids, such as omega-3 docosahexaenoic acid, omega-6 linoleic arachidonic in brains patients with schizophrenia. Methods: We summarize literature related postulated mechanistic connection between trials testing schizophrenia. Results Discussion: Fatty play critical roles cell membranes neurons, certain appear be abnormally low schizophrenia. The attempt enhance endogenous thus seems a rational worthwhile goal. value intervention awaits results ongoing trials. What new Conclusion: Despite limited supplements schizophrenia, given risk harm, some clinicians might opt add acid current drug regimens hope better symptomatic control
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