作者: J. Visser-van Balen
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摘要: Growing up with short stature. Psychosocial consequences of hormone treatment To enhance height in children stature, growth (GH) can be used. In without a detectable pathology underlying their there is no medical rationale for treatment. order to justify this but otherwise healthy children, it shown that being associated psychosocial problems and improves functioning. adolescence, better effects on are expected when combined puberty delaying (Gonadotropin Releasing Hormone Agonist, GnRHa). The administration makes the evaluation more important, as pubertal development temporarily arrested adolescents who already disadvantaged because height. This thesis examines children. literature regarding impact idiopathic stature (ISS) functioning ISS was reviewed discussed. From review concluded medically referred subgroup with, average according parents, than taller peers never visited pediatrician. adaptation probably depends presence or absence risk- protective factors, has hardly been studied. does not provide evidence GH treatment, which leads moderate variable gain, ISS. GnRHa 38 persistent born small gestational age (SGA) prospectively examined randomized controlled trial. Before GH/GnRHa SGA reported normal functioning, whereas parents worries about children's current behavior future chances finding spouse proper job. During three years indications some adverse treated were found. suggests useful monitor during SGA. young adulthood, both untreated participants showed compared Dutch population norms. Height gain 2.3 centimeters group. It that, long term independent adequate adjustment case results plead against adolescents. If will lead making decision an individual child matter weighing pros cons. worthwhile consider interventions instead adjunct