Dietary patterns and the risk of colorectal adenoma recurrence in a European intervention trial.

摘要: The relations between individual foods and nutrients to colorectal tumours are conflicting. Few studies have taken into account the interdependence components of diet their possible interactions. aim study was examine associations dietary patterns risk adenoma recurrence in European fibre-calcium intervention trial. Among 640 patients with confirmed adenomas at index colonoscopy, 592 had an initial assessment using a history questionnaire. present analysis restricted 277 men 165 women without prior colonoscopy who completed study. main end point 3-year adenomas. Principal component used identify from 50 food groups. Ninety-two presented new (65 27 women). In men, three meaningful emerged analysis, explaining 21.3% variability. They were called 'Mediterranean', 'Sweets snacks' 'High fat proteins' patterns. None them significantly related overall either univariate or multivariate analyses. women, 'Western' 'Snacks' explained 21.9% 'Mediterranean' pattern characterized by high consumption olive oil, vegetables, fruit, fish lean meat reduced [second tertile: adjusted odds ratio (OR)=0.50, 95% confidence interval (CI)=0.18-1.42; third OR=0.30, CI=0.09-0.98; P for linear trend=0.04]. not associated among women. conclusion, this suggests that Mediterranean may reduce adenomas, least These exploratory results need be larger studies.