Nutritional efficacy and hepatic changes during intragastric, intravenous, and prehepatic feeding in rats

作者: Walter W.-K. King , Roelof U. Boelhouwer , Andrew N. Kingsnorth , Jeffrey S. Ross , Vernon R. Young

DOI: 10.1177/0148607183007005443

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摘要: The nutritional efficacy and hepatic changes in rats given a total parenteral nutrition (TPN) solution consisting of 4.25% amino acids 25% dextrose by intragastric, intravenous, or prehepatic routes were studied over 4-day period. Rats fed Purina Chow intragastric TPN maintained body weight showed no appreciable fatty change liver. In contrast, loss, hepatomegaly, 37% increase liver lipid content observed intravenous 60% after TPN. Approximately half the developed Serum albumin concentration protein not improved SGOT SGPT elevated only. Prehepatic may result injury offers apparent benefit conventional rats. (Journal Parenteral Enteral Nutrition7: 443-446, 1983)

参考文章(10)
Lila Miller, Jean Anne Houghton, THE MICRO-KJELDAHL DETERMINATION OF THE NITROGEN CONTENT OF AMINO ACIDS AND PROTEINS Journal of Biological Chemistry. ,vol. 159, pp. 373- 383 ,(1945) , 10.1016/S0021-9258(19)52798-3
Carey P. Page, Man the Meal-Eater and His Interaction With Parenteral Nutrition JAMA: The Journal of the American Medical Association. ,vol. 244, pp. 1950- 1953 ,(1980) , 10.1001/JAMA.1980.03310170048026
Keith D. Lindor, Liver Function Values in Adults Receiving Total Parenteral Nutrition JAMA: The Journal of the American Medical Association. ,vol. 241, pp. 2398- 2400 ,(1979) , 10.1001/JAMA.1979.03290480032019
JESSE F. SCOTT, ALBA P. FRACCASTORO, EDGAR B. TAFT, Studies in histochemistry. I. Determination of nucleic acids in microgram amounts of tissue. Journal of Histochemistry and Cytochemistry. ,vol. 4, pp. 1- 10 ,(1956) , 10.1177/4.1.1
Susan Lanza-Jacoby, Harry S. Sitren, Nancy R. Stevenson, Francis E. Rosato, Changes in circadian rhythmicity of liver and serum parameters in rats fed a total parenteral nutrition solution by continuous and discontinuous intravenous or intragastric infusion. Journal of Parenteral and Enteral Nutrition. ,vol. 6, pp. 496- 502 ,(1982) , 10.1177/0148607182006006496
John T. Goodgame, Stephen F. Lowry, Murray F. Brennan, Body weight change and nutritional adequacy in the parenterally alimented rat Journal of Surgical Research. ,vol. 24, pp. 520- 526 ,(1978) , 10.1016/0022-4804(78)90051-3
George F. Sheldon, Hepatic Dysfunction During Hyperalimentation Archives of Surgery. ,vol. 113, pp. 504- 508 ,(1978) , 10.1001/ARCHSURG.1978.01370160162028
Jordi Folch, M. Lees, G.H. Sloane Stanley, A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES Journal of Biological Chemistry. ,vol. 226, pp. 497- 509 ,(1957) , 10.1016/S0021-9258(18)64849-5