ACE Inhibition with moexipril: a review of potential effects beyond blood pressure control.
作者： Amos Pines , Enrique Z Fisman
DOI: 10.2165/00129784-200303050-00006
关键词:
摘要: ACE inhibitors induce metabolic changes and exert cardioprotective vasoprotective properties, some of which cannot be attributed to their antihypertensive effect per se. Moexipril is an inhibitor with a lipophilicity in the same range as quinapril, benazepril or ramipril, so can readily penetrate lipid membranes thus target tissue addition plasma ACE. Evidence from animal studies shows similar significant (p ≪ 0.05) reductions activity for moexipril quinapril.
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