Molecular Epidemiology of Rabies Virus Isolates from Israel and Other Middle- and Near-Eastern Countries

作者: D. David , B. Yakobson , J. S. Smith , Y. Stram

DOI: 10.1128/JCM.38.2.755-762.2000

关键词:

摘要: A total of 226 isolates rabies virus from different areas Israel, including three human and one sample South Lebanon were identified between 1993 1998 by direct immunofluorescence using monoclonal antibodies to the viral nucleoprotein (N). An epidemiological survey based on nucleotide sequence analysis 328 bp C terminus N coding region noncoding phosphoprotein (NS gene) was performed. Phylogenetic Israel showed that they related geographically, but not according host species. Five variants, groups distributed among four geographical regions, identified. In each region, isolated more than animal comparison samples rest world revealed a 2-nucleotide change distinguished Middle East variants rest.

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