Liposarcoma: Advances in Cellular and Molecular Genetics Alterations and Corresponding Clinical Treatment.

摘要: Liposarcoma is a malignant tumor of mesenchymal origin with significant tissue diversity. It composed adipocytes different degrees differentiation and heteromorphosis. not sensitive to traditional radiotherapy chemotherapy has poor prognosis. In recent years, the rapid development basic immunology, molecular genetics biology, histological classification liposarcoma become increasingly clear. More more new methods technologies, such as gene expression profile analysis, whole genome sequencing, miRNA analysis RNA have been successfully applied liposarcoma, bringing about deeper understanding changes pathogenic mechanisms in occurrence liposarcoma. This study reviews present research status progress cellular alterations corresponding clinical treatment progress.