Inhibition of p70 s6 kinase

作者: Barbara E. Bierer , Joseph Avruch

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摘要: A method of screening for an antiproliferative or immunosuppressive agent, which includes the steps (1) contacting a eukaryotic cell with candidate composition; and (2) determining level activity serine/threonine kinase phosphatase in p70 S6 cascade said presence composition, wherein that results lower composition than absence is indication agent; methods treatment using such compositions.

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