The cost-effectiveness of universal screening in pregnancy for subclinical hypothyroidism
作者： Stephen F. Thung , Edmund F. Funai , William A. Grobman
DOI: 10.1016/J.AJOG.2008.10.035
关键词:
摘要: Objective The purpose of this study was to determine whether routine screening for subclinical hypothyroidism during pregnancy would be cost-effective. Study Design We developed a decision analysis model compare the cost-effectiveness 2 strategies hypothyroidism: (1) no serum thyroid-stimulating hormone (TSH) levels (standard) and (2) TSH levels. In latter, women with received thyroid replacement. assumed that replacement could reduce incidence an offspring IQ Results Our predicts universal is dominant strategy. For every 100,000 pregnant who were screened, $8,356,383 are saved, 589.3 QALYs gained. When prevalence reduced 0.25%, remains cost-effective at $21,664/QALY Conclusion Screening in will strategy under wide range circumstances.
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