Chemokines and Helicobacter pylori Infection

摘要: Helicobacter pylori is a spiral Gram-negative bacterium that chronically infects the gastroduodenal mucosal surface of humans (Fig. 1). Since initial successful culture H. in early 1980s, and appreciation this causative agent chronic gastritis (74, 111),the major role organism plays disease has become apparent. Although many infected subjects remain asymptomatic, very strong association with peptic ulcer was quickly established, bacterial eradication markedly reduces incidence recurrence (18). Subsequent studies detailed an between infection gastric mucosa-associated lymphoid tissue-type lymphoma (6, 56, 84, 115) adenocarcinoma (4, 25, 50, 83, 86, 106).