Gender Specificity of Body Adiposity and Circulating Adiponectin, Visfatin, Insulin, and Insulin Growth Factor-I at Term Birth: Relation to Prenatal Growth

作者: Lourdes Ibáñez , Giorgia Sebastiani , Abel Lopez-Bermejo , Marta Díaz , Maria Dolores Gómez-Roig

DOI: 10.1210/JC.2008-0526

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摘要: Context: Fetal development is thought to be gender specific for adiposity and circulating insulin IGF-I but not adipokinemia, as judged by serum visfatin adiponectin at term birth. We studied the potential relationship between these specificities fetal growth. Setting: The study was conducted a university hospital. Study Population: Subjects included 96 strictly matched neonates born appropriate gestational age (AGA; 24 girls, boys) or small (SGA; boys). Main Outcomes: Outcomes insulin, IGF-I, visfatin, total high-molecular-weight (HMW) adiponectin, osteocalcin birth, neonatal body composition absorptiometry. Results: Cord levels were higher in girls than boys (P ≤ 0.01), both AGA SGA subpopulation. In newborns, fat lean mass each < 0.0001), whereas HMW not. Conversely, adiponec...

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