Antimicrobial resistance and incompatibility groups of R plasmids in Salmonella typhimurium isolated from human sources in Bombay from 1978 to 1980.

摘要: Salmonella typhimurium isolated in Bombay from fecal samples of 145 patients suffering gastroenteritis (group 1) and the cerebrospinal fluid, feces, or blood 42 with systemic salmonellosis 2) were examined for antimicrobial resistance incompatibility groups their R plasmids. Multiple drug was encountered 88.9% isolates group 1 all 2. The found mainly against ampicillin, chloramphenicol, kanamycin, streptomycin, sulfonamides, tetracycline. In addition to these resistances, a number also resistant sulfamethoxazole-trimethoprim gentamicin. overall isolation frequency strains last drugs significantly higher 95.3% 2 plasmid mediated. Incompatibility grouping plasmids phage typing indicated that clone S. type pattern 66/122/untypable carrying Tra- IncF1me, Inc1, Inc2 most prevalent 1978 1980, examples this clone, especially those gentamicin, often responsible severe septicemic infection. A majority remaining untypable harbored IncC, IncFII, IncH1, IncH2, IncI1 IncI2; rarely associated