Multiple Primary Tumors of the Brain: Review of the Literature and Report of Twenty-one Cases

摘要: One phase in the study of new growths which has attracted considerable interest recent years is that concerned with multiple primary tumors. Although we cannot fully appreciate significance this phenomenon at present time, a available facts serves least to give some depth our conceptions as biology neoplasias. In more restricted field tumors nervous system and its envelopes, superficial or deep nerves have particular attention form von Recklinghausen's disease. While, from time reports isolated cases tissues themselves appeared, no serious effort been made review literature on subject analyze information collected cases. Having had unusual opportunity studying post-mortem specimens 21 gliomas brain,1 writer thought it worth while record his own findings accumulated data presented by these him literature. Borst (1) classified multicentric origin an anatomic basis follows: ( ) single organ, b bilateral symmetrically developing organs, c d functionally related e entirely different unrelated organs. By adapting classification arising intracranial tissues, following groups may be distinguished: one lobe hemisphere brain, both cerebral hemispheres, central system, brain associated others nerve roots meninges, finally space distant organs tissues. Since are especially (gliomas), only word will said passing regarding last two groups.