Role of Eicosanoids and the Cytokine Network in Transmembrane Signaling in Vascular Cells

作者: Kenneth B. Pomerantz , David P. Hajjar

DOI: 10.1007/978-1-4684-6024-7_10

关键词:

摘要: The concept that atherosclerosis is an inflammatory response to injury based on observations cells of monocytic origin, including macrophages and T-cells populate the developing atherosclerotic lesion. This in addition well-characterized smooth muscle cell infiltrate1. Since endothelial activation or a prerequisite for monocyte adhesion diapedesis, histologic evidence described above support hypothesis important initial event development Activation may thus initiate series process lead intimai hyperplasia choiesteryl ester deposition within macrophage cell.

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