The ultra long-term treatment of senile osteoporosis with 1α-hydroxyvitamin D3

作者: Masataka Shiraki , Hideki Ito , Hajime Orimo

DOI: 10.1016/S0169-6009(08)80003-7

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摘要: Summary We have attempted to examine the effects of long-term treatment with lα-hydroxyvitamin D3 (lα-OHD3; 0.5-1.0 μg/day) on bone and chemical parameters in osteoporosis, retrospectively. Twenty-six pairs age-, period observation- initial mineral density-matched patients or without were selected from 86 osteoporosis. An 11% decrease (-2.2%/year) a 6% increase radial density at peripheral cortical site was observed control treated group after 5 years, respectively (P

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