Sleep and Synaptic Plasticity in the Developing and Adult Brain
作者： Marcos G. Frank
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摘要: Sleep is hypothesized to play an integral role in brain plasticity. This has traditionally been investigated using behavioral assays. In the last 10–15 years, studies combining sleep measurements with vitro and vivo models of synaptic plasticity have provided exciting new insights into how alters strength. addition, theories proposed that integrate older ideas about function recent discoveries field There remain, however, important challenges unanswered questions. For example, does not appear a single effect on An unbiased review literature indicates effects vary widely depending ontogenetic stage, type waking experience (or stimulation protocols) precede neuronal synapse under examination. this review, I discuss these key findings context current posit different roles for
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