Radiofrequency Ablation for Eradication of Pulmonary Tumor in Rabbits
作者： Yi Miao , Yicheng Ni , Hilde Bosmans , Jie Yu , Johan Vaninbroukx
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摘要: Abstract Background. Radiofrequency ablation (RFA) has emerged as an alternative for surgery in clinical oncology. This animal experiment was conducted to evaluate the feasibility of RFA treatment pulmonary tumor. Methods. Eighteen rabbits with implantation VX2 tumors were divided into two groups. Group A (n = 12) treated by using a cooled-tip electrode technique. B 6) received sham operation. The therapeutic efficacy evaluated survival rate, magnetic resonance imaging (MRI), postmortem microangiography, and histology. Results. All animals group died within 3 months after tumor implantation. Tumor eradication achieved 9 12 (75.0%) A, which 4 survived longer than free disease another 5 found viable when sacrificed. One rabbit subjected incomplete suffered from local relapse and/or lung metastasis. 3-month rate RFA-treated significantly higher (P Conclusions. Eradication could be current technique rabbits. MRI is useful modality assessment ablation.
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