SUMOylation mediates the nuclear translocation and signaling of the IGF-1 receptor.

作者: B. Sehat , A. Tofigh , Y. Lin , E. Trocme , U. Liljedahl

DOI: 10.1126/SCISIGNAL.2000628

关键词:

摘要: … transfected HEK 293 cells with plasmids encoding wild-type IGF-1R … panel: HEK 293 cells were cotransfected with the reporter … 1 (IRS-1), which is important for the activation of IGF-1R–…

参考文章(61)
Ronald T. Hay, SUMO: a history of modification Molecular Cell. ,vol. 18, pp. 1- 12 ,(2005) , 10.1016/J.MOLCEL.2005.03.012
Haim Werner, Derek LeRoith, The Role of the Insulin-like Growth Factor System in Human Cancer Advances in Cancer Research. ,vol. 68, pp. 183- 223 ,(1996) , 10.1016/S0065-230X(08)60354-1
Ola Söderberg, Karl-Johan Leuchowius, Massood Kamali-Moghaddam, Malin Jarvius, Sigrun Gustafsdottir, Edith Schallmeiner, Mats Gullberg, Jonas Jarvius, Ulf Landegren, Proximity ligation: a specific and versatile tool for the proteomic era. Genetic engineering. ,vol. 28, pp. 85- 93 ,(2007) , 10.1007/978-0-387-34504-8_5
Timo Lassmann, ErikLL Sonnhammer, Kalign – an accurate and fast multiple sequence alignment algorithm BMC Bioinformatics. ,vol. 6, pp. 298- 298 ,(2005) , 10.1186/1471-2105-6-298
Svetlana Favelyukis, Jeffrey H. Till, Stevan R. Hubbard, W. Todd Miller, Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nature Structural & Molecular Biology. ,vol. 8, pp. 1058- 1063 ,(2001) , 10.1038/NSB721
Leonard Girnita, Sudha K. Shenoy, Bita Sehat, Radu Vasilcanu, Daiana Vasilcanu, Ada Girnita, Robert J. Lefkowitz, Olle Larsson, β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression Journal of Biological Chemistry. ,vol. 282, pp. 11329- 11338 ,(2007) , 10.1074/JBC.M611526200
Chiao-Wen Chen, Deodutta Roy, Up-regulation of nuclear IGF-I receptor by short term exposure of stilbene estrogen, diethylstilbestrol Molecular and Cellular Endocrinology. ,vol. 118, pp. 1- 8 ,(1996) , 10.1016/0303-7207(96)03751-3
Manuel S. Rodriguez, Joana M. P. Desterro, Sonia Lain, Carol A. Midgley, David P. Lane, Ronald T. Hay, SUMO‐1 modification activates the transcriptional response of p53 The EMBO Journal. ,vol. 18, pp. 6455- 6461 ,(1999) , 10.1093/EMBOJ/18.22.6455
Renato Baserga, The IGF-I receptor in cancer research. Experimental Cell Research. ,vol. 253, pp. 1- 6 ,(1999) , 10.1006/EXCR.1999.4667