Endoscopic gastric cancer screening and surveillance in high-risk groups.

摘要: Gastric cancer remains a major problem world-wide and future incidence will likely increase due to rapidly aging population demographics. Population-based screening is being undertaken in Korea Japan, where gastric rates are high, seems be effective reducing mortality from cancer. However, such strategies difficult implement countries with low or limited resources. Thus, should directed towards high-risk subgroups. has relatively long mean sojourn time, prognosis of early-stage disease excellent. In general population, at 2-year interval for diagnosis. subjects atrophic gastritis intestinal metaplasia, surveillance recommended 1 3 years intervals according European Japanese recommendation. Screening family members sporadic not yet been adequately evaluated, but 1-year hereditary diffuse family-members. patients treated by endoscopic resection the highest-risk group, can detect most metachronous cancers an early stage. Future using endoscopy guided risk-stratification assessment, further refinement optimal needed.