Dynamics of T Lymphocyte Responses: Intermediates, Effectors, and Memory Cells
作者： Antonio Lanzavecchia , Federica Sallusto
DOI: 10.1126/SCIENCE.290.5489.92
关键词:
摘要: The immune response is initiated in organized lymphoid tissues where antigen-loaded dendritic cells (DCs) encounter antigen-specific T cells. DCs function as packets of information that must be decoded by the cell before an appropriate can mounted. We discuss how dynamics DC-T and mechanism differentiation make decoding this stochastic rather than determinate. This results generation both terminally differentiated effector intermediates play distinctive roles protection, immunoregulation, immunological memory.
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harvard.edu参考文章(120)
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