Transcutaneous blood gas monitoring in the rat

摘要: Transcutaneous blood gas (TCBG) analysis is a noninvasive alternative method of estimation tensions. The objective the study reported here was to validate this against standard (STBG) in adult and juvenile Sprague-Dawley rats. We sought establish optimal TCBG probe site temperature, temperatures that would not cause thermal burns, evaluate correlations between values (PaCO2 PaO2) determined by use STBG, sensitivity unit changes arterial partial pressures. Our results indicated that: general, xyphoid area for placement, with 44.5 degrees C being temperature highest correlation, but burns may be problem; 42.5 (adults) 42.0 (juveniles) do when left place three hours; 44 42 resulted moderate correlation PaCO2 PtcCO2; adequately responded Neither PtcCO2 or PtcO2 reflect actual PaO2, respectively. concluded used as an indicator change sufficient animal numbers under tightly controlled conditions, PaO2