Analysis of Prognosis in Colorectal Mucinous Adenocarcinoma: A Retrospective Analysis with Peritoneal Fluid

作者: Seung Bong Choi , In Kyu Lee , Dae Youn Won , Yoon Suk Lee , Yoon Si

DOI: 10.4174/JKSS.2010.79.6.474

关键词:

摘要: Purpose: Although many papers have reported poor prognosis of colorectal mucinous adenocarcinoma, the underlying cause for its unfavorable outcome is yet to be elucidated. In peritoneal fluid studies, we observed that recurrences and cytology positive cases were times cancers. On basis these observations, non-mucinous adenocarcinomas compared prognostic factors studied. Methods: Five hundred forty-six patients who underwent surgery from January 2004 December 2008 included. Results: Among 546 patients, 30 (5.5%) 516 (94.5%). Mean age was 55.0 years, which younger than 63.2 years in colon They tend develop right colon. Mucinous more advanced depth invasion distant metastasis, but no significant difference lymph node (LN) metastasis. Peritoneal CEA, CA19-9, apparent. Liver metastasis did not show increases. year survival rates 82.9% 91.7% cancer free 42.7% 68.5% each, respectively, According stage, only stage Ⅲ Ⅳ showed differences overall (P=0.001, 0.040). Conclusion: worse prognoses recurrences, had similar early LN dissimilarities infiltration depth. Infiltrations led increase cells tumor markers: ultimately developed.

参考文章(27)
Robey-Cafferty Ss, Cleary Kr, Connelly Jh, Mucinous carcinomas of the colon and rectum. An analysis of 62 stage B and C lesions. Archives of Pathology & Laboratory Medicine. ,vol. 115, pp. 1022- 1025 ,(1991)
I. Kanellos, E. Zacharakis, D. Kanellos, M.-G. Pramateftakis, D. Betsis, Prognostic significance of CEA levels and positive cytology in peritoneal washings in patients with colorectal cancer. Colorectal Disease. ,vol. 8, pp. 436- 440 ,(2006) , 10.1111/J.1463-1318.2006.00991.X
Bruce D. Minsky, Carolyn Mies, Tyvin A. Rich, Abram Recht, John T. Chaffey, Colloid carcinoma of the colon and rectum Cancer. ,vol. 60, pp. 3103- 3112 ,(1987) , 10.1002/1097-0142(19871215)60:12<3103::AID-CNCR2820601241>3.0.CO;2-6
H. C. Umpleby, D. L. Ranson, R. C. N. Williamson, Peculiarities of mucinous colorectal carcinoma. British Journal of Surgery. ,vol. 72, pp. 715- 718 ,(2005) , 10.1002/BJS.1800720915
In Kyu Lee, Do Hyoung Kim, D. Lee Gorden, Yoon Suk Lee, Na Young Sung, Gyeoung-Sin Park, Hyung Jin Kim, Won Kyung Kang, Jong Kyung Park, Chang Hyeok Ahn, Jun-Gi Kim, Hae Myung Jeon, Seong Taek Oh, Prognostic value of CEA and CA 19-9 tumor markers combined with cytology from peritoneal fluid in colorectal cancer. Annals of Surgical Oncology. ,vol. 16, pp. 861- 870 ,(2009) , 10.1245/S10434-008-0294-3
G.B. Secco, R. Fardelli, E. Campora, G. Lapertosa, R. Gentile, S. Zoli, C. Prior, Primary mucinous adenocarcinomas and signet-ring cell carcinomas of colon and rectum. Oncology. ,vol. 51, pp. 30- 34 ,(1994) , 10.1159/000227306
I. Kanellos, H. Demetriades, E. Zintzaras, A. Mandrali, I. Mantzoros, D. Betsis, Incidence and prognostic value of positive peritoneal cytology in colorectal cancer Diseases of The Colon & Rectum. ,vol. 46, pp. 535- 539 ,(2003) , 10.1007/S10350-004-6595-0
Kab Choong Kim, Duck-Woo Kim, Hyung Chul Park, Jae-Gahb Park, Mucinous Adenocarcinoma of the Colon and Rectum Journal of the Korean Society of Coloproctology. ,vol. 23, pp. 60- 64 ,(2007) , 10.3393/JKSC.2007.23.1.60
Daniel A. Symonds, Austin L. Vickery, Mucinous carcinoma of the colon and rectum Cancer. ,vol. 37, pp. 1891- 1900 ,(1976) , 10.1002/1097-0142(197604)37:4<1891::AID-CNCR2820370439>3.0.CO;2-Z
Yukihide Kanemitsu, Tomoyuki Kato, Takashi Hirai, Kenzo Yasui, Takeshi Morimoto, Yasuhiro Shimizu, Yasuhiro Kodera, Yoshitaka Yamamura, Survival after curative resection for mucinous adenocarcinoma of the colorectum. Diseases of The Colon & Rectum. ,vol. 46, pp. 160- 167 ,(2003) , 10.1007/S10350-004-6518-0