Recent progress and advances in redox-responsive polymers as controlled delivery nanoplatforms

作者: Xiaoyong Zhang , Lu Han , Meiying Liu , Ke Wang , Lei Tao

DOI: 10.1039/C6QM00135A

关键词:

摘要: Stimuli-responsive polymeric nanosystems that can respond to biological stimuli such as pH, temperature, glucose, enzymes or redox conditions have been extensively explored for different biomedical applications. Among these, should be the most useful stimulus in systems, which rely on significantly states circulation/extracellular fluids and intracellular compartments. By incorporation of redox-responsive linkages disulfide diselenide into polymers, fabricated. In this review article, a number therapeutic their design principles are included. Recent advances these controlled cytoplasmic delivery bioactive molecules (e.g. drugs, proteins, plasmid DNA, siRNA) also highlighted. This will provide information applications nanosystems, attract great research interest from scientists chemistry, materials, biology, medicine interdisciplinary areas.

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