Specific cytotoxic activity of T lymphocyte clones derived from a patient with gliosarcoma
作者： Shin-Ichi Miyatake , Haruhiko Kikuchi , Kohichi Iwasaki , Junkoh Yamashita , Yuzirou Namba
DOI: 10.3171/JNS.1988.69.5.0751
关键词:
摘要: ✓ Eleven lymphocyte clones were established from the peripheral blood lymphocytes of a patient with gliosarcoma by means autologous tumor stimulation and limiting-dilution technique recombinant interleukin-2. Ten 11 cytotoxic against cell line GI-1. Seven 10 also allogeneic brain-tumor lines HeLa cells, one clone was several target two specifically GI-1 cells. One not any cells tested. Lymphokine-activated killer induced interleukin-2 alone exhibited activity all Surface phenotypic analysis revealed that expressed CD3 antigen, some CD4 others CD8 antigen. These seemed to be antigen-specific T clones. Analysis these c...
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