作者: P. J. J. Becker , J. Hegelbach , L. F. Keller , E. Postma
DOI: 10.1111/JEB.12759
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摘要: Inbreeding depression is usually quantified by regressing individual phenotypic values on inbreeding coefficients, implicitly assuming there no correlation between an individual's phenotype and the kinship coefficient to its mate. If such association parental exists, if trait of interest heritable, estimates can be biased. Here we first derive expected bias as a function covariance mean breeding value kinship. Subsequently, use simulated data confirm existence this bias, show that it accounted for in quantitative genetic animal model. Finally, long-term individual-based white-throated dippers (Cinclus cinclus), bird species which relatively common, obtain empirical estimate bias. We during part study period, parents inbred birds had shorter wings than those outbred birds, wing length individuals were smaller, independent any effects. This resulted overestimation Similarly, period when longer wings, found effects underestimated. discuss how associations may have arisen system, why they are likely occur others, too. Overall, demonstrate less biased obtained within framework, suggest additive should simultaneously whenever possible.