Sickle cell disease--pathophysiology, clinical and diagnostic implications.
作者： Alexandra Dorn-Beineke , Thomas Frietsch
关键词:
摘要: We review the current knowledge of pathophysiology sickle cell disease (SCD), clinical complications and state art in SCD diagnostics. Today, a flexible laboratory concept allows fast economic clarification patients' hemoglobin (HbS) status, e.g. additional compound heterozygosities. In contrast to well-investigated disease, factors influencing severity symptoms as well some findings still lack final explanation. this review, we focus on red lysis resistance an diagnostic tool SCD. There is need for further studies regarding blood samples from patients with HbS.
sci-hub.se 参考文章(63)
O Castro, DJ Brambilla, B Thorington, CA Reindorf, RB Scott, P Gillette, JC Vera, PS Levy, The acute chest syndrome in sickle cell disease: incidence and risk factors. The Cooperative Study of Sickle Cell Disease Blood. ,vol. 84, pp. 643- 649 ,(1994) , 10.1182/BLOOD.V84.2.643.BLOODJOURNAL842643
Yvonne F. Posey, Dinesh Shah, Janet E. Ulm, K. Tyrone Bastin, Fritz F. Pari, John A. Phillips, Prenatal diagnosis of sickle cell anemia: hemoglobin electrophoresis versus DNA analysis American Journal of Clinical Pathology. ,vol. 92, pp. 347- 351 ,(1989) , 10.1093/AJCP/92.3.347
Robert S. Schwartz, Sylvia Musto, Mary E. Fabry, Ronald L. Nagel, Two distinct pathways mediate the formation of intermediate density cells and hyperdense cells from normal density sickle red blood cells Blood. ,vol. 92, pp. 4844- 4855 ,(1998) , 10.1182/BLOOD.V92.12.4844
N Fortier, LM Snyder, F Garver, C Kiefer, J McKenney, N Mohandas, The relationship between in vivo generated hemoglobin skeletal protein complex and increased red cell membrane rigidity. Blood. ,vol. 71, pp. 1427- 1431 ,(1988) , 10.1182/BLOOD.V71.5.1427.1427
Quentin J Franklin, Michael Compeggie, Splenic syndrome in sickle cell trait: four case presentations and a review of the literature. Military Medicine. ,vol. 164, pp. 230- 233 ,(1999) , 10.1093/MILMED/164.3.230
FM Gill, LA Sleeper, SJ Weiner, AK Brown, R Bellevue, R Grover, CH Pegelow, E Vichinsky, Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative Study of Sickle Cell Disease. Blood. ,vol. 86, pp. 776- 783 ,(1995) , 10.1182/BLOOD.V86.2.776.BLOODJOURNAL862776
D D Suh, J S Krauss, K Bures, Influence of hemoglobin S adducts on hemoglobin A2 quantification by HPLC. Clinical Chemistry. ,vol. 42, pp. 1113- 1114 ,(1996) , 10.1093/CLINCHEM/42.7.1113
KR Bridges, GD Barabino, C Brugnara, MR Cho, GW Christoph, G Dover, BM Ewenstein, DE Golan, CR Guttmann, J Hofrichter, RV Mulkern, B Zhang, WA Eaton, A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy Blood. ,vol. 88, pp. 4701- 4710 ,(1996) , 10.1182/BLOOD.V88.12.4701.BLOODJOURNAL88124701
BD Smith, PL La Celle, Erythrocyte-endothelial cell adherence in sickle cell disorders. Blood. ,vol. 68, pp. 1050- 1054 ,(1986) , 10.1182/BLOOD.V68.5.1050.1050
Darren P. Wirthwein, Sheila D. Spotswood, Jeffrey J. Barnard, Joseph A. Prahlow, Death due to microvascular occlusion in sickle-cell trait following physical exertion. Journal of Forensic Sciences. ,vol. 46, pp. 399- 401 ,(2001) , 10.1520/JFS14982J