Aryl and heterocyclic substituted propenamide derivatives

作者: Karnail S. Atwal , Syed Z. Ahmed , Dinos P. Santafianos

DOI:

关键词:

摘要: Novel compounds useful, for example, the treatment of ischemic conditions and arrhythmia are disclosed. The have formula ##STR1## wherein X is oxygen or sulfur R groups as defined herein.

参考文章(22)
Karnail Atwal, Indane and quinoline derivatives ,(1991)
Gary James Grover, Karnail Atwal, Kyoung Soon Kim, Pyranyl cyanoguanidine derivatives ,(1992)
Robert W. Lang, Paul F. Wenk, Synthesis of selectively trifluoromethylated pyridine derivaties as potential antihypertensives Helvetica Chimica Acta. ,vol. 71, pp. 596- 601 ,(1988) , 10.1002/HLCA.19880710312
C. R. Rasmussen, F. J. Villani, Jr., L. E. Weaner, B. E. Reynolds, A. R. Hood, L. R. Hecker, S. O. Nortey, A. Hanslin, M. J. Costanzo, E. T. Powell, A. J. Molinari, Improved Procedures for the Preparation of Cycloalkyl-, Arylalkyl-, and Arylthioureas Synthesis. ,vol. 1988, pp. 456- 459 ,(1988) , 10.1055/S-1988-27605
John M. Evans, Charles S. Fake, Thomas C. Hamilton, Robert H. Poyser, Eric A. Watts, Synthesis and antihypertensive activity of substituted trans-4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ols. Journal of Medicinal Chemistry. ,vol. 26, pp. 1582- 1589 ,(1983) , 10.1021/JM00365A007
Valerie A. Ashwood, Robin E. Buckingham, Frederick Cassidy, John M. Evans, Erol A. Faruk, Thomas C. Hamilton, David J. Nash, Geoffrey Stemp, Kenneth Willcocks, Synthesis and antihypertensive activity of 4-(cyclic amido)-2H-1-benzopyrans. Journal of Medicinal Chemistry. ,vol. 29, pp. 2194- 2201 ,(1986) , 10.1021/JM00161A011
Asoke Banerji, Naresh C. Goomer, Enolates of o-hydroxyacetophenones: novel synthesis of 2,2-dialkyl-4-chromanones Tetrahedron Letters. ,vol. 20, pp. 3685- 3686 ,(1979) , 10.1016/S0040-4039(01)95497-8