Rapid lung MRI in children with pulmonary infections: Time to change our diagnostic algorithms.

作者: Kushaljit Singh Sodhi , Niranjan Khandelwal , Akshay Kumar Saxena , Meenu Singh , Ritesh Agarwal

DOI: 10.1002/JMRI.25082

关键词:

摘要: Background To determine the diagnostic utility of a new rapid MRI protocol, as compared with computed tomography (CT) for detection various pulmonary and mediastinal abnormalities in children suspected infections. Methods Seventy-five (age range 5 to 15 years) clinically infections were enrolled this prospective study, which was approved by institutional ethics committee. All patients underwent thoracic (1.5T) CT (64 detector) scan within 48 h each other. The sensitivity, specificity, positive predictive value (PPV), negative (NPV) evaluated standard reference. Inter-observer agreement measured kappa coefficient. Results MRI protocol demonstrated PPV, NPV 100% detecting consolidation, nodules (>3 mm), cyst/cavity, hyperinflation, pleural effusion, lymph nodes. kappa-test showed almost perfect between multidetector (MDCT) (k = 0.9). No statistically significant difference observed MDCT McNemar test (P 0.125). Conclusion Rapid lung found be comparable pediatric infections. It has great potential first line cross-sectional imaging modality choice patient population. However, further studies will helpful confirmation our findings. J. Magn. Reson. Imaging 2015.

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