A mixed methods approach to adapting health-related quality of life measures for use in routine oncology clinical practice

摘要: The current study reviewed and adapted existing health-related quality of life (HRQoL) instruments for use in routine clinical practice delivering outpatient chemotherapy colorectal, breast gynaecological cancers. 564 (288 gynaecological, 208 68 colorectal) consultations 141 patients were audio-recorded analysed to identify discussed issues. Issues ranked from most least commonly within each disease group. Existing HRQoL evaluated against these lists best fitting items entered into cancer-specific item banks. Item banks during semi-structured interviews by twenty-one oncologists (13 consultants 8 specialist registrars), four nurse specialists thirty patients, breast, colorectal cancer practices. Pilot questionnaires completed 448 (145 148 155 attending clinics. selection scale reliability was explored using descriptive data psychometric methods alongside qualitative patient clinician ratings. Each questionnaire includes five physical three psychosocial function scales with good internal consistency (α > 0.70) plus disease-specific individual-symptom identified as useful practice. Three measures developed Initial analyses suggest utility acceptable properties the new instruments.