Nursery rearing of infant monkeys (Macaca fascicularis) for toxicity studies.

摘要: At birth, nine infant male cynomolgus monkeys (Macaca fascicularis) weighed an average of 402 g and 16 female 362 g. Both infants last 15-20 by the fourth day after birth. Female showed a growth rate approximately 4 5 body wt/day, respectively, from to 150 days age. Caloric intake increased 140 cal/gkg weight/day in both females males on first birth peak values 325 290 cal/kg males, subsequently declined about 200 cal/kg/day 250 for females. Total calories consumed per 53 cal/day 68 60 age males. Erythrocyte counts, packed cell volume, hemoglobin decreased 2 weeks age, then stabilized. An increase lymphocyte count, with concomitant decrease mature neutrophils, was observed 6 "Temper fits" certain aggressive behavioral signs were as early 3-4 began develop social orders 30-40th day. Behavioral abnormalities frequently seen reared isolation not observed.