Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis.
作者： Javier Fernández , Miquel Navasa , Ramón Planas , Silvia Montoliu , David Monfort
DOI: 10.1053/J.GASTRO.2007.06.065
关键词:
摘要: Background & Aims: Norfloxacin is highly effective in preventing spontaneous bacterial peritonitis recurrence cirrhosis, but its role the primary prevention of this complication uncertain. Methods: Patients with cirrhosis and low protein ascitic levels ( Results: administration reduced 1-year probability developing (7% vs 61%, P = .02), improved 3-month (94% 62%, .003) (60% 48%, .05) survival compared placebo. Conclusions: Primary prophylaxis norfloxacin has a great impact clinical course patients advanced cirrhosis. It reduces incidence peritonitis, delays development hepatorenal syndrome, improves survival.
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Tilman M. Bauer, Antonio Follo, Miguel Navasa, Jordi Vila, Ramon Planas, Gerardo Clemente, Victor Vargas, Felipe Bory, Pere Vaquer, Juan Rodés, Daily norfloxacin is more effective than weekly rufloxacin in prevention of spontaneous bacterial peritonitis recurrence. Digestive Diseases and Sciences. ,vol. 47, pp. 1356- 1361 ,(2002) , 10.1023/A:1015386901343
Bruce A. Runyon, Low-protein-concentration ascitic fluid is predisposed to spontaneous bacterial peritonitis Gastroenterology. ,vol. 91, pp. 1343- 1346 ,(1986) , 10.1016/0016-5085(86)90185-X
Montserrat Andreu, Ricard Sola, Antonio Sitges-Serra, Concepcion Alia, Manuel Gallen, M.Carmen Vila, Susana Coll, Maria Isabel Oliver, Risk factors for spontaneous bacterial peritonitis in cirrhotic patients with ascites Gastroenterology. ,vol. 104, pp. 1133- 1138 ,(1993) , 10.1016/0016-5085(93)90284-J
Josep Llach, Pere Ginès, Vicente Arroyo, Antoni Rimola, Llúcia Titó, Salvatore Badalamenti, Wladimiro Jiménez, Joan Gaya, Francisca Rivera, Joan Rodés, Prognostic value of arterial pressure, endogenous vasoactive systems, and renal function in cirrhotic patients admitted to the hospital for the treatment of ascites Gastroenterology. ,vol. 94, pp. 482- 487 ,(1988) , 10.1016/0016-5085(88)90441-6
Pere Ginés, Antoni Rimola, Ramón Planas, Victor Vargas, Francesc Marco, Manuel Almela, Montserrat Forne, Maria Luisa Miranda, Josep Llach, Joan Manuel Salmerón, Maria Esteve, Josep Maria Marques, Maria Teresa Jiménez de Anta, Vicente Arroyo, Joan Rodés, Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: Results of a double‐blind, placebo‐controlled trial Hepatology. ,vol. 12, pp. 716- 724 ,(1990) , 10.1002/HEP.1840120416
Nina Singh, Trimethoprim-Sulfamethoxazole for the Prevention of Spontaneous Bacterial Peritonitis in Cirrhosis Annals of Internal Medicine. ,vol. 122, pp. 595- 598 ,(1995) , 10.7326/0003-4819-122-8-199504150-00007
Ramon Planas, Silvia Montoliu, Belen Ballesté, Monica Rivera, Mireia Miquel, Helena Masnou, Jose Antonio Galeras, María D. Giménez, Justiniano Santos, Isabel Cirera, Rosa María Morillas, Susanna Coll, Ricard Solà, Natural history of patients hospitalized for management of cirrhotic ascites. Clinical Gastroenterology and Hepatology. ,vol. 4, pp. 1385- 1394 ,(2006) , 10.1016/J.CGH.2006.08.007
Paolo Angeli, Florence Wong, Hugh Watson, Pere Ginès, , Hyponatremia in cirrhosis: Results of a patient population survey Hepatology. ,vol. 44, pp. 1535- 1542 ,(2006) , 10.1002/HEP.21412
M Novella, R Sola, G Soriano, M Andreu, J Gana, J Ortiz, S Coll, M Sabat, M C Vila, C Guarner, F Vilardell, Continuous versus inpatient prophylaxis of the first episode of spontaneous bacterial peritonitis with norfloxacin Hepatology. ,vol. 25, pp. 532- 536 ,(1997) , 10.1002/HEP.510250306
Javier Fernández, Miquel Navasa, Juliá Gómez, Jordi Colmenero, Jordi Vila, Vicente Arroyo, Juan Rodés, Bacterial infections in cirrhosis: Epidemiological changes with invasive procedures and norfloxacin prophylaxis Hepatology. ,vol. 35, pp. 140- 148 ,(2002) , 10.1053/JHEP.2002.30082