Molecularly imprinted solid-phase extraction coupled with gas chromatography for the determination of four chloroacetamide herbicides in soil

摘要: A molecularly imprinted solid phase extraction (MISPE) coupled with gas chromatography (GC) for the simultaneous separation and determination of four chloroacetamide herbicides, alachlor, acetochlor, pretilachlor metolachlor, in soil was developed. Molecularly polymers (MIPs) butachlor as dummy template were synthesized via precipitation polymerization, where methacrylic acid (MAA) used functional monomer, ethylene glycol dimethacrylate (EDMA) crosslinker acetonitrile porogen. Fourier-transform infrared spectrometry (FTIR) scanning electron microscopy (SEM) to characterize polymers. Under optimum SPE conditions, polymer sorbents can selectively extract enrich metolachlor. comparison experiment also showed that MISPE cartridges better than nonimprinted C18 terms recovery. The mean recoveries herbicides from blank spiked at 0.1, 0.5, 1 μg mL−1 ranged between 80.6 90.2% relative standard deviations (RSD) less 8% (n = 5). limit detection (LOD) quantification (LOQ) analytes range 1.0 × 10−12 5 10−11 g 0.0005–0.025 mg kg−1, respectively. presented MISPE-GC method exhibited highly selective enrichment trace could be potentially applied soil.