Thioketals and thioethers for inhibiting the expression of VCAM-1

作者: Patricia K. Somers , Charles Q. Meng , Lee K. Hoong

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摘要: Thioketals and thioethers are provided that inhibit the expression of VCAM-1, which can be used in treatment VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular autoimmune neurological cancer. The compounds also to treat hyperlipidemia and/or hypercholesterolemia.

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