Encapsulation of Antioxidants in Gastrointestinal-Resistant Nanoparticulate Carriers

作者: Eliana B. Souto , Patrícia Severino , Rafael Basso , Maria Helena A. Santana

DOI: 10.1007/978-1-62703-475-3_3

关键词:

摘要: Reactive oxygen species (ROS) are known to cause several human pathologies. For this reason, antioxidants have gained utmost importance because of their potential as prophylactic and therapeutic agents in many diseases. Examples application include use diabetic patients, aging drugs, cancer diseases, Parkinson's, Alzheimer's, autoimmune disorders, also inflammation. Antioxidants limited absorption profiles, therefore low bioavailability concentrations at the target site. Efforts been done towards loading antioxidant molecules advanced nanoparticulate carriers, e.g., liposomes, polymeric nanoparticles, solid lipid self-emulsifying drug delivery system. -successful achievements encapsulation drugs other active ingredients, coenzyme Q10, vitamin E A, resveratrol polyphenols, curcumin, lycopene, silymarin, superoxide dismutase. This review focuses on comprehensive analysis using carriers for these oral administration.

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