Regulation of G-Protein-Coupled Receptor (GPCR) Trafficking in the Striatum in Parkinson’s Disease
作者： Marie-Laure Martin-Negrier , Céline Guigoni , Bertrand Bloch , Erwan Bézard
DOI: 10.1007/978-1-60327-252-0_17
关键词:
摘要: Abbreviations GABA: gamma-aminobutyric acid, GPCR: G-protein-coupled receptor, GRK: G-protein-linked receptor kinase, MAPK: mitogen-activated protein D1R: dopamine 1, DR5: 5, D2R: 2, D3R: 3, D4R: 4, cAMP: adenosine 3’,5’-cyclic monophosphate, PD: Parkinson’s disease, 6-OH-DA: 6-hydroxydopamine, LID: levodopa-induced dyskinesia, MPTP:1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, DA: dopamine, NMDAR: N-methyl-D-aspartate NR1: NMDA subunit NR2A: 2A, NR2B: 2B, DARPP32: dopamineand cAMP-regulated phosphoprotein 32 kDa, PSD95: postsynaptic density protein-95, PSD:
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