作者: Ramesh K. Khurana , J. M. Petras
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摘要: The sensory innervation of the postpharyngeal foregut was investigated by injecting enzyme horseradish peroxidase (HRP) into walls esophagus, stomach, or duodenum. transported HRP identified histochemically, labeled neurons in spinal and vagal ganglia were counted, results plotted using an SAS statistical program. fields each viscus defined three determinations: craniocaudal extent, principal field, peak field. data revealed that are craniocaudally extensive, field overlaps significantly with its neighbor, yet can be characterized a density. Craniocaudal esophagus spans as many 22-23 paired (C1-L2). There two for cervical (C2-C6 T2-T4) thoracic (T2-T4 T8-T12) sectors esophagus. stomach extends over 25 (C2-L5). large area comprising cranial, middle, immediately adjoining caudal (T2-T10). duodenum is innervated 15 thoracolumbar (T2-L3). Peak originates middle cranial lumbar (T6-L1) ganglia. recognizable viscerotopic organization foregut; successively more this region alimentary canal supplied fibers from dorsal root Vagal afferent bilateral predominantly, but not exclusively, vast numbers nodose (distal) bilaterally abundantly jugular (proximal) than either physiological significance findings discussed relation to phenomena visceral pain referred pain.